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Endonuclease-mediated Allele Detail
Symbol: Clba1em1(IMPC)J
Name: clathrin binding box of aftiphilin containing 1; endonuclease-mediated mutation 1, Jackson
MGI ID: MGI:7446962
Gene: Clba1  Location: Chr12:112772595-112779865 bp, + strand  Genetic Position: Chr12, 61.2 cM
Alliance: Clba1em1(IMPC)J page
IMPC: Clba1 gene page
Strain of Origin:  C57BL/6NJ
Project Collection: IMPC
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCACATCTAAAACCCTGTCG and CTTAGCTCGGAACTGCGCCG, which resulted in a 378 bp deletion beginning at Chromosome 12 position 112,774,279 bp and ending after 112,774,656 bp (GRCm39/mm39). This mutation deletes ENSMUSE00000306390 (exon 2) and 241 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 140 and early truncation 1 amino acids later. (J:188991)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Clba1 Mutation:  8 strains or lines available
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory