Cdh5em1(nigri)Bzsh
Endonuclease-mediated Allele Detail
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Symbol: |
Cdh5em1(nigri)Bzsh |
Name: |
cadherin 5; endonuclease-mediated mutation 1, Bin Zhou |
MGI ID: |
MGI:7444934 |
Synonyms: |
Cdh5-Nigri |
Gene: |
Cdh5 Location: Chr8:104828257-104871143 bp, + strand Genetic Position: Chr8, 53.04 cM
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Alliance: |
Cdh5em1(nigri)Bzsh page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Null/knockout, Recombinase) |
Mutation: |
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Insertion
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Cdh5em1(nigri)Bzsh expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Using CRISPR/Cas9 methods, a cDNA encoding the Nigri (recombinase identified and isolated from bacteria sp Vibrio nigripulchritudo) cassette was inserted into the second exon of the Cdh5 gene.
(J:266564)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cdh5
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cdh5 Mutation: |
53 strains or lines available
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Original: |
J:266564 Liu K, et al., A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development. 2018 Sep 17;145(18):dev167775 |
All: |
1 reference(s) |
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