Peli1^tm1Yhli
Targeted Allele Detail

Summary

• Symbol: Peli1^tm1Yhli
• Name: pellino 1; targeted mutation 1, Yuehua Li
• MGI ID: MGI:7444816
• Synonyms: Peli1^Flox
• Gene: Peli1 Location: Chr11:21041291-21100323 bp, + strand Genetic Position: Chr11, 13.81 cM, cytoband A3.2
• Alliance: Peli1^tm1Yhli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229292
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 3 and inserted an FRT-flanked neomycin resistance cassette into intron 3. (J:229292)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Peli1 Mutation: 32 strains or lines available

References

• Original: J:229292 Wu W, et al., Silencing of Pellino1 improves post-infarct cardiac dysfunction and attenuates left ventricular remodelling in mice. Cardiovasc Res. 2014 Apr 1;102(1):46-55
• All: 4 reference(s)