Fancl^em1Gaof
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fancl^em1Gaof
• Name: Fanconi anemia, complementation group L; endonuclease-mediated mutation 1, Fei Gao
• MGI ID: MGI:7444813
• Gene: Fancl Location: Chr11:26337084-26421883 bp, + strand Genetic Position: Chr11, 15.85 cM, cytoband A2-A3
• Alliance: Fancl^em1Gaof page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting created a point deletion in exon 1 that introduces a new stop codon. (J:333943)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fancl Mutation: 28 strains or lines available

References

• Original: J:333943 Cen C, et al., Fancb deficiency causes premature ovarian insufficiency in mice. Biol Reprod. 2022 Sep 12;107(3):790-799
• All: 1 reference(s)