Rtel1tm4.1(cre/ERT2)Hdin
Targeted Allele Detail
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Symbol: |
Rtel1tm4.1(cre/ERT2)Hdin |
Name: |
regulator of telomere elongation helicase 1; targeted mutation 4.1, Hao Ding |
MGI ID: |
MGI:7442434 |
Synonyms: |
Rtel1CreERT2, Rtel1-CreERT2 |
Gene: |
Rtel1 Location: Chr2:180961532-180998409 bp, + strand Genetic Position: Chr2, 103.63 cM
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Alliance: |
Rtel1tm4.1(cre/ERT2)Hdin page
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Mutations: |
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Insertion, Intragenic deletion
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Rtel1tm4.1(cre/ERT2)Hdin expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A FRT flanked SA-IRESbgeo cassette, and T2A-CreERT2 replaced the exon 7 of the Rtel1 gene. The FRT flanked SA-IRESbgeo cassette was removed by Flpe-mediated recombination.
(J:267997)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Rtel1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rtel1 Mutation: |
75 strains or lines available
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Original: |
J:267997 Seshadri N, et al., Generation of an Rtel1-CreERT2 knock-in mouse model for lineage tracing RTEL1+ stem cells during development. Transgenic Res. 2018 Dec;27(6):571-578 |
All: |
1 reference(s) |
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