Mgp^em1Borr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mgp^em1Borr
• Name: matrix Gla protein; endonuclease-mediated mutation 1, Teresa Borras
• MGI ID: MGI:7442303
• Synonyms: Mgp.floxed
• Gene: Mgp Location: Chr6:136849433-136852821 bp, - strand Genetic Position: Chr6, 66.72 cM
• Alliance: Mgp^em1Borr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 3 and 4 of the gene are flanked by loxP sites using CRISPR/cas9 methodologies. (J:298926)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mgp Mutation: 11 strains or lines available

References

• Original: J:298926 Borras T, et al., Generation of a Matrix Gla (Mgp) floxed mouse, followed by conditional knockout, uncovers a new Mgp function in the eye. Sci Rep. 2020 Oct 29;10(1):18583
• All: 1 reference(s)