Tie1^{tm1c(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Tie1^{tm1c(KOMP)Wtsi}
• Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1; targeted mutation 1c, Wellcome Trust Sanger Institute
• MGI ID: MGI:7442217
• Synonyms: Tie1^flx
• Gene: Tie1 Location: Chr4:118328388-118347046 bp, - strand Genetic Position: Chr4, 54.67 cM
• Alliance: Tie1^{tm1c(KOMP)Wtsi} page
• IMPC: Tie1 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333808
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tie1 Mutation: 69 strains or lines available

References

• Original: J:333808 Du J, et al., Endothelial Tyrosine Kinase Tie1 Is Required for Normal Schlemm's Canal Development-Brief Report. Arterioscler Thromb Vasc Biol. 2022 Mar;42(3):348-351
• All: 1 reference(s)