Npffr1^tm1.1Gand
Targeted Allele Detail

Summary

• Symbol: Npffr1^tm1.1Gand
• Name: neuropeptide FF receptor 1; targeted mutation 1.1, Greg M Anderson
• MGI ID: MGI:7439915
• Gene: Npffr1 Location: Chr10:61431271-61464344 bp, + strand Genetic Position: Chr10, 32.24 cM
• Alliance: Npffr1^tm1.1Gand page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333702
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 4 and inserted a floxed neomycin resistance cassette, IRES, and EGFP reporter gene. Recombination removed the selection cassette. (J:333702)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npffr1 Mutation: 20 strains or lines available

References

• Original: J:333702 Anderson G, Chemogenetic activation of RFRP neurons stimulates behavioural stress responses in male but not female mice. MGI Direct Data Submission. 2023
• All: 1 reference(s)