Satb2^{tm1.1(cre/ERT2)Slp}
Targeted Allele Detail

Summary

• Symbol: Satb2^{tm1.1(cre/ERT2)Slp}
• Name: special AT-rich sequence binding protein 2; targeted mutation 1.1, Samuel L Pfaff
• MGI ID: MGI:7439756
• Synonyms: atb2-CreERdeltaneo, Satb2-CreER
• Gene: Satb2 Location: Chr1:56833140-57017809 bp, - strand Genetic Position: Chr1, 28.72 cM
• Alliance: Satb2^{tm1.1(cre/ERT2)Slp} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:260688
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Satb2^{tm1.1(cre/ERT2)Slp} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Satb2 (MGI:2679336)

• Mutation details: A Cre-ER/WPRE/polyA/FRT-neo-FRT cassette was inserted into the ATG of the Satb2 locus. Positive founders were crossed with the FLPe deleter mouse line to eliminate the neo cassette. (J:260688)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Satb2 (mouse) Summary of all recombinase alleles driven by Satb2. Comparative matrix view of recombinase activities Alliance mouse Satb2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Satb2 Mutation: 43 strains or lines available

References

• Original: J:260688 Hilde KL, et al., Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb Position. Neuron. 2016 Aug 17;91(4):763-776
• All: 1 reference(s)