Vwf^{em1(cre/ERT2)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vwf^{em1(cre/ERT2)Cya}
• Name: Von Willebrand factor; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7439361
• Synonyms: Vwf-CreERT2, Vwf^{tm1.1(cre/ERT2)Cya}
• Gene: Vwf Location: Chr6:125529911-125663642 bp, + strand Genetic Position: Chr6, 59.32 cM
• Alliance: Vwf^{em1(cre/ERT2)Cya} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase, Reporter)
• Mutation: Insertion
• Vwf^{em1(cre/ERT2)Cya} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vwf (MGI:98941)

• Mutation details: An IRES-CreERT2-P2A-eGFP cassette was inserted into 3 UTR of the endogenous Vwf gene. eGFP expression was not detectable in these mice. (J:257748)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vwf (mouse) Summary of all recombinase alleles driven by Vwf. Comparative matrix view of recombinase activities Alliance mouse Vwf gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vwf Mutation: 139 strains or lines available

References

• Original: J:257748 Carrelha J, et al., Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells. Nature. 2018 Feb 1;554(7690):106-111
• All: 1 reference(s)