Ptn^{tm1(cre/ERT2)Zjh}
Targeted Allele Detail

Summary

• Symbol: Ptn^{tm1(cre/ERT2)Zjh}
• Name: pleiotrophin; targeted mutation 1, Z Josh Huang
• MGI ID: MGI:7438130
• Synonyms: Ptn-CreER
• Gene: Ptn Location: Chr6:36691863-36787114 bp, - strand Genetic Position: Chr6, 15.48 cM
• Alliance: Ptn^{tm1(cre/ERT2)Zjh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252096
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Ptn^{tm1(cre/ERT2)Zjh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ptn (MGI:97804)

• Mutation details: A targeting vector was designed to insert a CreERT2 fusion gene followed by an frt-flanked neo cassette, at the stop codon of the Ptn gene. (J:252096)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ptn (mouse) Summary of all recombinase alleles driven by Ptn. Comparative matrix view of recombinase activities Alliance mouse Ptn gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ptn Mutation: 14 strains or lines available

References

• Original: J:252096 Paul A, et al., Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity. Cell. 2017 Oct 19;171(3):522-539.e20
• All: 1 reference(s)