Dcp2^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dcp2^em1Bcgen
• Name: decapping mRNA 2; endonuclease-mediated mutation 1, Biocytogen LLC
• MGI ID: MGI:7435311
• Gene: Dcp2 Location: Chr18:44513569-44558036 bp, + strand Genetic Position: Chr18, 23.74 cM, cytoband B3
• Alliance: Dcp2^em1Bcgen page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: CRISPR-cas9 mediated recombination inserted an IRES-EGFP cassette into the 3' UTR 17 nucleotides downstream of the stop codon. (J:321231)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcp2 Mutation: 41 strains or lines available

References

• Original: J:321231 Zhang MN, et al., MicroRNA-141-3p/200a-3p target and may be involved in post-transcriptional repression of RNA decapping enzyme Dcp2 during renal development. Biosci Biotechnol Biochem. 2018 Oct;82(10):1724-1732
• All: 1 reference(s)