Ebf1^tm1.1Tng
Targeted Allele Detail

Summary

• Symbol: Ebf1^tm1.1Tng
• Name: early B cell factor 1; targeted mutation 1.1, Takashi Nagasawa
• MGI ID: MGI:7435185
• Synonyms: Ebf1^f
• Gene: Ebf1 Location: Chr11:44508144-44898918 bp, + strand Genetic Position: Chr11, 26.45 cM
• Alliance: Ebf1^tm1.1Tng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271945
• Parent Cell Line: KY1.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted an FRT-flanked neomycin resistance cassette with a 5' loxP site upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. (J:271945)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ebf1 Mutation: 74 strains or lines available

References

• Original: J:271945 Seike M, et al., Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Genes Dev. 2018 Mar 1;32(5-6):359-372
• All: 1 reference(s)