Celsr2^em1Ddev
Endonuclease-mediated Allele Detail

Summary

• Symbol: Celsr2^em1Ddev
• Name: cadherin, EGF LAG seven-pass G-type receptor 2; endonuclease-mediated mutation 1, Danelle Devenport
• MGI ID: MGI:7434999
• Gene: Celsr2 Location: Chr3:108298167-108323383 bp, - strand Genetic Position: Chr3, 47.02 cM
• Alliance: Celsr2^em1Ddev page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated an 81 bp deletion that includes the start codon and the first 9 codons of the signal sequence. (J:333055)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celsr2 Mutation: 114 strains or lines available

References

• Original: J:333055 Basta LP, et al., Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity. Front Cell Dev Biol. 2022;10:1064907
• All: 1 reference(s)