Mfsd2a^{tm2(cre/ERT2)Dls}
Targeted Allele Detail

Summary

• Symbol: Mfsd2a^{tm2(cre/ERT2)Dls}
• Name: MFSD2 lysolipid transporter A, lysophospholipid; targeted mutation 2, David L Silver
• MGI ID: MGI:7434664
• Synonyms: Mfsd2a-CreERT2, Mfsd2aERT2cre
• Gene: Mfsd2a Location: Chr4:122840643-122854981 bp, - strand Genetic Position: Chr4, 57.34 cM, cytoband D1
• Alliance: Mfsd2a^{tm2(cre/ERT2)Dls} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333161
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Not Specified
• Mfsd2a^{tm2(cre/ERT2)Dls} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mfsd2a (MGI:1923824)

• Mutation details: The allele was generated by inserting tamoxifen-inducible cre (ERT2cre) into exon 1 of the Mfsd2a gene. (J:333161)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mfsd2a (mouse) Summary of all recombinase alleles driven by Mfsd2a. Comparative matrix view of recombinase activities Alliance mouse Mfsd2a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mfsd2a Mutation: 37 strains or lines available

References

• Original: J:333161 Wong BH, et al., The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis. J Biol Chem. 2022 Feb 9;:101709
• All: 3 reference(s)