Tiparp^tm1Aki
Targeted Allele Detail

Summary

• Symbol: Tiparp^tm1Aki
• Name: TCDD-inducible poly(ADP-ribose) polymerase; targeted mutation 1, Shizuo Akira
• MGI ID: MGI:7434574
• Gene: Tiparp Location: Chr3:65435868-65462939 bp, + strand Genetic Position: Chr3, 30.2 cM
• Alliance: Tiparp^tm1Aki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241588
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exon 2 with a neomycin resistance cassette. (J:241588)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tiparp Mutation: 44 strains or lines available

References

• Original: J:241588 Kozaki T, et al., Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proc Natl Acad Sci U S A. 2017 Mar 07;114(10):2681-2686
• All: 1 reference(s)