Fgf10^em1Smy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fgf10^em1Smy
• Name: fibroblast growth factor 10; endonuclease-mediated mutation 1, Ian M Smyth
• MGI ID: MGI:7433184
• Synonyms: tm1
• Gene: Fgf10 Location: Chr13:118851199-118928651 bp, + strand Genetic Position: Chr13, 67.14 cM, cytoband A3-A4
• Alliance: Fgf10^em1Smy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRIPSR/Cas9 technology targeting exon 3 generated a 7 bp duplication and 140 bp deletion (c.464_470dup; 506_645del). (J:311447)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgf10 Mutation: 32 strains or lines available

References

• Original: J:311447 Teague WJ, et al., FGF10 and the Mystery of Duodenal Atresia in Humans. Front Genet. 2018;9:530
• All: 1 reference(s)