Synb^em1(cre)Mdf
Endonuclease-mediated Allele Detail

Summary

• Symbol: Synb^em1(cre)Mdf
• Name: syncytin b; endonuclease-mediated mutation 1, Mark D Fleming
• MGI ID: MGI:7433162
• Synonyms: SynbCre
• Gene: Synb Location: Chr14:69526793-69531748 bp, - strand Genetic Position: Chr14, 36.04 cM
• Alliance: Synb^em1(cre)Mdf page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Synb^em1(cre)Mdf expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Synb (MGI:3045308)

• Mutation details: Using CRISPR targeting, 2A (P2A) and Cre were inserted immediately before the stop codon of the Synb gene. (J:331974)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Synb (mouse) Summary of all recombinase alleles driven by Synb. Comparative matrix view of recombinase activities Alliance mouse Synb gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Synb Mutation: 7 strains or lines available

References

• Original: J:331974 Cao C, et al., Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy. Development. 2022 Dec 1;149(23):dev201160
• All: 1 reference(s)