About   Help   FAQ
Hoxa13tm1.1(cre)Mlkn
Targeted Allele Detail
Summary
Symbol: Hoxa13tm1.1(cre)Mlkn
Name: homeobox A13; targeted mutation 1.1, Mark L Kahn
MGI ID: MGI:7433099
Synonyms: Hoxa13Cre
Gene: Hoxa13  Location: Chr6:52235833-52237865 bp, - strand  Genetic Position: Chr6, 25.41 cM
Alliance: Hoxa13tm1.1(cre)Mlkn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:332098
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Hoxa13tm1.1(cre)Mlkn expression driven by 1 gene
 
Mutation detailsA T2A-fused Cre coding region, and a flippase recombination target (FRT)flanked WPRE-pA and neomycin resistance cassette were inserted into the exon 2 of the Hoxa13 gene. FLPo recombinase removed the sequences flanked by FRT sites, which includes neo cassette, exogenous PolyA and WPRE. (J:332098)
Recombinase
activity
Activity:
Loading...
Driver: Hoxa13 (mouse)
Summary of all recombinase alleles driven by Hoxa13.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa13 Mutation:  29 strains or lines available
References
Original:  J:332098 Chen X, et al., Mouse placenta fetal macrophages arise from endothelial cells outside the placenta. Dev Cell. 2022 Dec 5;57(23):2652-2660.e3
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory