Slc12a8em2(cre/ERT2)Imai
Endonuclease-mediated Allele Detail
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Symbol: |
Slc12a8em2(cre/ERT2)Imai |
Name: |
solute carrier family 12 (potassium/chloride transporters), member 8; endonuclease-mediated mutation 2, Shin-ichiro Imai |
MGI ID: |
MGI:7432978 |
Synonyms: |
Slc12a8-CreERT2 |
Gene: |
Slc12a8 Location: Chr16:33337698-33484505 bp, + strand Genetic Position: Chr16, 24.12 cM
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Alliance: |
Slc12a8em2(cre/ERT2)Imai page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Slc12a8em2(cre/ERT2)Imai expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The P2A followed by cre/ERT2 sequence was inserted downstream of the Slc12a8 gene by CRISPR/Cas9 system.
(J:333074)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Slc12a8
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc12a8 Mutation: |
32 strains or lines available
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Original: |
J:333074 Ito N, et al., Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging. Cell Rep. 2022 Jul 26;40(4):111131 |
All: |
1 reference(s) |
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