Shoc1^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Shoc1^em2Smoc
• Name: shortage in chiasmata 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
• MGI ID: MGI:7432964
• Synonyms: Shoc1^{em1(flox)Smoc}, Shoc1^f
• Gene: Shoc1 Location: Chr4:59043753-59138983 bp, - strand Genetic Position: Chr4, 32.36 cM
• Alliance: Shoc1^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 5. (J:331352)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shoc1 Mutation: 51 strains or lines available

References

• Original: J:331352 Wang W, et al., Bi-allelic variants in SHOC1 cause non-obstructive azoospermia with meiosis arrest in humans and mice. Mol Hum Reprod. 2022 May 27;28(6)
• All: 1 reference(s)