Cxcr3^tm2Arsa
Targeted Allele Detail

Summary

• Symbol: Cxcr3^tm2Arsa
• Name: C-X-C motif chemokine receptor 3; targeted mutation 2, Abhay R Satoskar
• MGI ID: MGI:7432859
• Synonyms: Cxcr3^RFP
• Gene: Cxcr3 Location: ChrX:100775141-100777753 bp, - strand Genetic Position: ChrX, 44.58 cM
• Alliance: Cxcr3^tm2Arsa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279686
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector is designed to insert an internal ribosome entry site (IRES), tdTomato fluorescent protein, and bovine growth hormone polyadenylation sequence, followed by an loxP-flanked neomycin resistance cassette, downstream of exon 2. (J:279686)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcr3 Mutation: 12 strains or lines available

References

• Original: J:279686 Oghumu S, et al., Cutting Edge: CXCR3 Escapes X Chromosome Inactivation in T Cells during Infection: Potential Implications for Sex Differences in Immune Responses. J Immunol. 2019 Aug 15;203(4):789-794
• All: 1 reference(s)