Arx^em1Sjm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Arx^em1Sjm
• Name: aristaless related homeobox; endonuclease-mediated mutation 1, Sean J Morrison
• MGI ID: MGI:7432849
• Synonyms: ARX^fl
• Gene: Arx Location: ChrX:92330113-92341963 bp, + strand Genetic Position: ChrX, 41.05 cM
• Alliance: Arx^em1Sjm page

Mutation origin

• Strain of Origin: C57BL/Ka

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Using CRISPR-targeting, the exon 3 flanked by loxp sites was generated. (J:333068)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arx Mutation: 21 strains or lines available

References

• Original: J:333068 Burgess RJ, et al., Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells. Genes Dev. 2022 Aug 1;36(15-16):887-900
• All: 1 reference(s)