Misfa^em4Kei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Misfa^em4Kei
• Name: mitochondrial sheath formation associated; endonuclease-mediated mutation 4, Keiichi I Nakayama
• MGI ID: MGI:7432749
• Synonyms: Polluks-FLAG
• Gene: Misfa Location: Chr7:46633328-46637551 bp, + strand Genetic Position: Chr7, 30.66 cM
• Alliance: Misfa^em4Kei page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting inserted a FLAG-tag at the C-terminus of the Polluks transcript (J:332977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Misfa Mutation: 0 strains or lines available

References

• Original: J:332977 Mise S, et al., Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis. Nat Commun. 2022 Feb 28;13(1):1071
• All: 1 reference(s)