Tcof1^tm1.1Patr
Targeted Allele Detail

Summary

• Symbol: Tcof1^tm1.1Patr
• Name: treacle ribosome biogenesis factor 1; targeted mutation 1.1, Paul A Trainor
• MGI ID: MGI:7432644
• Synonyms: Tcof1^flx
• Gene: Tcof1 Location: Chr18:60946827-60982043 bp, - strand Genetic Position: Chr18, 34.41 cM
• Alliance: Tcof1^tm1.1Patr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332795
• Parent Cell Line: HZ2.2 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 1 was floxed and a selection cassette inserted via homologous recombination. Cre mediated recombination removed the selection cassette. (J:332795)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcof1 Mutation: 109 strains or lines available

References

• Original: J:332795 Falcon KT, et al., Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2116974119
• All: 1 reference(s)