Noxo1^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Noxo1^tm1.1Arte
• Name: NADPH oxidase organizer 1; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:7431417
• Synonyms: NoxO1-
• Gene: Noxo1 Location: Chr17:24915208-24919503 bp, + strand Genetic Position: Chr17, 12.49 cM, cytoband A3.3
• Alliance: Noxo1^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246999
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector inserted the loxp site, FRT flanked neo cassette upstream of exon 2, and a loxp site downstream of exon 9 through homologous recombination in C57/BL6 stem cells. The cre recombination generated a global null allele by the deletion of exons 2 to 9. (J:246999)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Noxo1 Mutation: 14 strains or lines available

References

• Original: J:246999 Brandes RP, et al., The Cytosolic NADPH Oxidase Subunit NoxO1 Promotes an Endothelial Stalk Cell Phenotype. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1558-65
• All: 3 reference(s)