Ifnlr1^em13Tkay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ifnlr1^em13Tkay
• Name: interferon lambda receptor 1; endonuclease-mediated mutation 13, Thomas Kay
• MGI ID: MGI:7431302
• Gene: Ifnlr1 Location: Chr4:135413598-135435492 bp, + strand Genetic Position: Chr4, 67.94 cM
• Alliance: Ifnlr1^em13Tkay page

Mutation origin

• Strain of Origin: NOD/ShiLtJArc

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology using sgRNA 5GAGTAGGGGCGCCCACCGGT-3 generated a 16 bp deletion. (J:325263)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifnlr1 Mutation: 38 strains or lines available

References

• Original: J:325263 Jhala G, et al., Interferons limit autoantigen-specific CD8(+) T-cell expansion in the non-obese diabetic mouse. Cell Rep. 2022 Apr 26;39(4):110747
• All: 1 reference(s)