Fzd6^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fzd6^em2Gpt
• Name: frizzled class receptor 6; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
• MGI ID: MGI:7431258
• Synonyms: Fzd6^Q152E
• Gene: Fzd6 Location: Chr15:38869673-38901587 bp, + strand
• Alliance: Fzd6^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting of exon 4 introduced the mutation responsible for the amino acid substitution of glutamine with glutamic acid at position (Q152E). (J:327324)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzd6 Mutation: 43 strains or lines available

References

• Original: J:327324 Han H, et al., Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive Symptoms. Front Mol Neurosci. 2022;15:882396
• All: 1 reference(s)