Sphk1^tm1Cya
Targeted Allele Detail

Summary

• Symbol: Sphk1^tm1Cya
• Name: sphingosine kinase 1; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7431248
• Synonyms: SphK1^flox
• Gene: Sphk1 Location: Chr11:116421751-116427501 bp, + strand Genetic Position: Chr11, 81.42 cM, cytoband E2
• Alliance: Sphk1^tm1Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327342
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exons 3 through 6. (J:327342)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sphk1 Mutation: 30 strains or lines available

References

• Original: J:327342 Yu J, et al., Generation of mice with hepatocyte-specific conditional deletion of sphingosine kinase 1. Transgenic Res. 2020 Aug;29(4):419-428
• All: 1 reference(s)