Il1rl2^tm1.1Llsm
Targeted Allele Detail

Summary

• Symbol: Il1rl2^tm1.1Llsm
• Name: interleukin 1 receptor-like 2; targeted mutation 1.1, Lloyd S Miller
• MGI ID: MGI:7430846
• Synonyms: IL-36R^fl
• Gene: Il1rl2 Location: Chr1:40363770-40406722 bp, + strand Genetic Position: Chr1, 18.96 cM
• Alliance: Il1rl2^tm1.1Llsm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332779
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 3 flanked by loxP sites. A neomycin cassette flanked by self-deletion anchor sites was self-excised. (J:332779)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il1rl2 Mutation: 45 strains or lines available

References

• Original: J:332779 Patrick GJ, et al., Epicutaneous Staphylococcus aureus induces IL-36 to enhance IgE production and ensuing allergic disease. J Clin Invest. 2021 Mar 1;131(5)
• All: 2 reference(s)