Rnf31^tm2.1Kiwa
Targeted Allele Detail

Summary

• Symbol: Rnf31^tm2.1Kiwa
• Name: ring finger protein 31; targeted mutation 2.1, Kazuhiro Iwai
• MGI ID: MGI:7429190
• Synonyms: Hoip^flox
• Gene: Rnf31 Location: Chr14:55829199-55841131 bp, + strand Genetic Position: Chr14, 28.19 cM
• Alliance: Rnf31^tm2.1Kiwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279330
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exons 7 through 11. Flp-mediated recombination removed the selection cassette. (J:279330)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rnf31 Mutation: 48 strains or lines available

References

• Original: J:279330 Sasaki K, et al., Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nat Commun. 2019 Aug 28;10(1):3878
• All: 2 reference(s)