Tg(CRBN)123Plbe
Transgene Detail
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| Symbol: |
Tg(CRBN)123Plbe |
| Name: |
transgene insertion 123, P Leif Bergsagel |
| MGI ID: |
MGI:7429138 |
| Synonyms: |
hC123 |
| Transgene: |
Tg(CRBN)123Plbe Location: unknown Genetic Position: Chr17, Syntenic
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| Alliance: |
Tg(CRBN)123Plbe page
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| Strain of Origin: |
C57BL/6J
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| Project Collection: |
APF ENU Mutagenesis
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CRBN)123Plbe involves 1 genes/genome features (Gm6741)
View all
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Tg(CRBN)123Plbe expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CRBN (51185) |
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Mutation details: The transgene contains human CTD-2335G19 (92kb hg38 chr3:3147091-3239264) containing the entire CRBN with additional regulatory regions. Line 123 was generated.
(J:308274)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:308274 Meermeier EW, et al., Tumor burden limits bispecific antibody efficacy through T cell exhaustion averted by concurrent cytotoxic therapy. Blood Cancer Discov. 2021 Jul;2(4):354-369 |
| All: |
2 reference(s) |
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Analysis Tools
