Pex7^tm2Nbra
Targeted Allele Detail

Summary

• Symbol: Pex7^tm2Nbra
• Name: peroxisomal biogenesis factor 7; targeted mutation 2, Nancy Braverman
• MGI ID: MGI:7428962
• Synonyms: Pex7^hypo, Pex7^tm2.0Nbra
• Gene: Pex7 Location: Chr10:19735836-19783420 bp, - strand Genetic Position: Chr10, 9.16 cM, cytoband A3
• Alliance: Pex7^tm2Nbra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327348
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, Hypomorph)
• Mutation: Insertion
• The targeting construct floxed exon 3 and introduced a neomycin resistance cassette. (J:327348)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pex7 Mutation: 16 strains or lines available

References

• Original: J:327348 Fallatah W, et al., A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity-Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1. Front Cell Dev Biol. 2022;10:886316
• All: 1 reference(s)