Gt(ROSA)26Sor^{tm1(EEF1A1-Mir182)Lifg}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(EEF1A1-Mir182)Lifg}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Feng Liu
• MGI ID: MGI:7428910
• Synonyms: miR-182-5p-Tg^flox
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(EEF1A1-Mir182)Lifg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327367
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct inserted into the locus a polyadenylation sequence, GFP reporter gene, loxP site, lox2272 site, EF1alpha promoter in reverse, loxP site, lox2272 site, microRNA sequence, and polyadenylation sequence. (J:327367)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:327367 Xiao T, et al., miR-182-5p promotes hepatocyte-stellate cell crosstalk to facilitate liver regeneration. Commun Biol. 2022 Aug 1;5(1):771
• All: 1 reference(s)