Tob1^em1Tya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tob1^em1Tya
• Name: transducer of ErbB-2.1; endonuclease-mediated mutation 1, Tadashi Yamamoto
• MGI ID: MGI:7428764
• Synonyms: Tob^fl
• Gene: Tob1 Location: Chr11:94102280-94106321 bp, + strand Genetic Position: Chr11, 58.9 cM, cytoband C
• Alliance: Tob1^em1Tya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:327375
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:327375)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tob1 Mutation: 31 strains or lines available

References

• Original: J:327375 Youssef MMM, et al., TOB is an effector of the hippocampus-mediated acute stress response. Transl Psychiatry. 2022 Jul 29;12(1):302
• All: 1 reference(s)