Kdm3a^tm1.1Yshk
Targeted Allele Detail

Summary

• Symbol: Kdm3a^tm1.1Yshk
• Name: lysine (K)-specific demethylase 3A; targeted mutation 1.1, Yoichi Shinkai
• MGI ID: MGI:7428612
• Synonyms: Jmjd1a^2lox, Kdm3a^tm1.1Mtac
• Gene: Kdm3a Location: Chr6:71565954-71609963 bp, - strand Genetic Position: Chr6, 32.18 cM
• Alliance: Kdm3a^tm1.1Yshk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:313942
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 22 and an FRT-flanked selection cassette and second loxP site were inserted downstream of exon 23. The selection cassette was removed via flp-mediated recombination leaving exons 22-23 floxed. (J:313942)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kdm3a Mutation: 82 strains or lines available

References

• Original: J:313942 Kuroki S, et al., H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline. Stem Cell Reports. 2020 Aug 11;15(2):424-438
• All: 1 reference(s)