Ift56^em1Kldr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ift56^em1Kldr
• Name: intraflagellar transport 56; endonuclease-mediated mutation 1, Klas Kullander
• MGI ID: MGI:7428506
• Synonyms: Ttc26^Y430X
• Gene: Ift56 Location: Chr6:38358404-38404582 bp, + strand Genetic Position: Chr6, 17.76 cM
• Alliance: Ift56^em1Kldr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Single point mutation
• Mutation details: CRISPR-cas9 mediated recombination created a C to A point mutation in exon 15 at position 38412065 bp resulting in a Y to STOP mutation at position 430. (J:321845)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ift56 Mutation: 30 strains or lines available

References

• Original: J:321845 Bernhardt N, et al., Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro. 2022 Mar-Apr;9(2):ENEURO.0518-21.2022
• All: 1 reference(s)