Mir22^em3Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir22^em3Smoc
• Name: microRNA 22; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7428494
• Synonyms: miR-22^flox
• Gene: Mir22 Location: Chr11:75354542-75354636 bp, + strand Genetic Position: Chr11, 45.91 cM
• Alliance: Mir22^em3Smoc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR-cas9 mediated recombination flanked the sequence with loxP sites. (J:322079)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir22 Mutation: 6 strains or lines available

References

• Original: J:322079 Lou P, et al., MiR-22 modulates brown adipocyte thermogenesis by synergistically activating the glycolytic and mTORC1 signaling pathways. Theranostics. 2021;11(8):3607-3623
• All: 2 reference(s)