Anxa6^em1Mcn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Anxa6^em1Mcn
• Name: annexin A6; endonuclease-mediated mutation 1, Elizabeth M McNally
• MGI ID: MGI:7427722
• Synonyms: Anxa6gfp
• Gene: Anxa6 Location: Chr11:54869934-54924271 bp, - strand Genetic Position: Chr11, 32.13 cM
• Alliance: Anxa6^em1Mcn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328260
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting replaced the STOP codon and 3'UTR with a linker sequence and TurboGFP reporter gene. (J:328260)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Anxa6 Mutation: 46 strains or lines available

References

• Original: J:328260 Demonbreun AR, et al., A conserved annexin A6-mediated membrane repair mechanism in muscle, heart, and nerve. JCI Insight. 2022 Jul 22;7(14):e158107
• All: 1 reference(s)