Psmb8^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Psmb8^tm1.1Geno
• Name: proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); targeted mutation 1.1, Genoway
• MGI ID: MGI:7427718
• Synonyms: LMP7 fl
• Gene: Psmb8 Location: Chr17:34417169-34420428 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: Psmb8^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:328265
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exon 3. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:328265)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psmb8 Mutation: 18 strains or lines available

References

• Original: J:328265 Dimasuay KG, et al., Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection. Sci Rep. 2022 Aug 25;12(1):14507
• All: 1 reference(s)