Usp26^em1Amp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp26^em1Amp
• Name: ubiquitin specific peptidase 26; endonuclease-mediated mutation 1, Alberto M Pendas
• MGI ID: MGI:7427708
• Synonyms: Usp26²¹
• Gene: Usp26 Location: ChrX:50842836-50890110 bp, - strand Genetic Position: ChrX, 28.31 cM
• Alliance: Usp26^em1Amp page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/J)F1/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR-cas9 mediated recombination using single guide RNA created two consecutive insertions of 85 bp and 19 bp. This results in a frameshift mutation with a premature STOP codon at position 123. (J:324507)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp26 Mutation: 7 strains or lines available

References

• Original: J:324507 Felipe-Medina N, et al., Ubiquitin-specific protease 26 (USP26) is not essential for mouse gametogenesis and fertility. Chromosoma. 2019 Sep;128(3):237-247
• All: 1 reference(s)