Nrgn^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Nrgn^m1Btlr
• Name: neurogranin; mutation 1, Bruce Beutler
• MGI ID: MGI:7427570
• Gene: Nrgn Location: Chr9:37455789-37464041 bp, - strand Genetic Position: Chr9, 20.78 cM
• Alliance: Nrgn^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C point mutation at 37546048 bp (GRCm38) that results in the amino acid substitution of serine with glycine at position 48 (S48G). (J:328845)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrgn Mutation: 8 strains or lines available

References

• Original: J:328845 Baranowski RW, et al., Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance. Biochem Biophys Res Commun. 2022 Oct 1;623:89-95
• All: 2 reference(s)