Trim13^em2Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim13^em2Smoc
• Name: tripartite motif-containing 13; endonuclease-mediated mutation2, Shanghai Model Organisms Center
• MGI ID: MGI:7427521
• Synonyms: Trim13^{em1(flox)Smoc}, Trim13^flox
• Gene: Trim13 Location: Chr14:61835696-61843395 bp, + strand Genetic Position: Chr14, 33.16 cM
• Alliance: Trim13^em2Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 3. (J:329154)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trim13 Mutation: 54 strains or lines available

References

• Original: J:329154 Li X, et al., The transmembrane endoplasmic reticulum-associated E3 ubiquitin ligase TRIM13 restrains the pathogenic-DNA-triggered inflammatory response. Sci Adv. 2022 Jan 28;8(4):eabh0496
• All: 1 reference(s)