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Stk25tm1Zhex
Targeted Allele Detail
Summary
Symbol: Stk25tm1Zhex
Name: serine/threonine kinase 25 (yeast); targeted mutation 1, Xiangjian Zheng
MGI ID: MGI:7427399
Gene: Stk25  Location: Chr1:93548473-93581937 bp, - strand  Genetic Position: Chr1, 47.25 cM
Alliance: Stk25tm1Zhex page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:324862
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site and FRT flanked neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 5 via homologous recombination. (J:324862)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk25 Mutation:  22 strains or lines available
References
Original:  J:324862 Wang R, et al., Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting. JCI Insight. 2021 Jun 22;6(12)
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory