Stk25^tm1Zhex
Targeted Allele Detail

Summary

• Symbol: Stk25^tm1Zhex
• Name: serine/threonine kinase 25 (yeast); targeted mutation 1, Xiangjian Zheng
• MGI ID: MGI:7427399
• Gene: Stk25 Location: Chr1:93548473-93581937 bp, - strand Genetic Position: Chr1, 47.25 cM
• Alliance: Stk25^tm1Zhex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324862
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 5 via homologous recombination. (J:324862)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk25 Mutation: 21 strains or lines available

References

• Original: J:324862 Wang R, et al., Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting. JCI Insight. 2021 Jun 22;6(12)
• All: 2 reference(s)