Cd55em1Cys
Endonuclease-mediated Allele Detail
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Symbol: |
Cd55em1Cys |
Name: |
CD55 molecule, decay accelerating factor for complement; endonuclease-mediated mutation 1, Jason G Cyster |
MGI ID: |
MGI:7427391 |
Gene: |
Cd55 Location: Chr1:130366764-130390481 bp, - strand Genetic Position: Chr1, 56.89 cM
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Alliance: |
Cd55em1Cys page
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: CRISPR-cas9 mediated recombination using guide RNAs (CTGGCATTAGGAATGTCTGG and TCTGTCTTGAAAATGGCCAA) created a 139 bp deletion in exon 2 in the Cd55 gene. The identical sequence was also deleted in the Cd55b gene resulting in Cd55bem1Cysi allele.
(J:324874)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cd55 Mutation: |
37 strains or lines available
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Original: |
J:324874 Liu D, et al., CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells. Science. 2022 Feb 11;375(6581):eabi5965 |
All: |
2 reference(s) |
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