Smarca2^em1Bbr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Smarca2^em1Bbr
• Name: SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2; endonuclease-mediated mutation 1, Benoit G Bruneau
• MGI ID: MGI:7425427
• Gene: Smarca2 Location: Chr19:26582578-26755721 bp, + strand Genetic Position: Chr19, 21.17 cM, cytoband C1
• Alliance: Smarca2^em1Bbr page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-cas9 mediated recombination using guide RNAs targeting exon 3 created a 4bp deletion in exon 3. (J:325945)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarca2 Mutation: 91 strains or lines available

References

• Original: J:325945 Hota SK, et al., Brahma safeguards canalization of cardiac mesoderm differentiation. Nature. 2022 Feb;602(7895):129-134
• All: 1 reference(s)