Cyp26b1^em1Nses
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cyp26b1^em1Nses
• Name: cytochrome P450, family 26, subfamily b, polypeptide 1; endonuclease-mediated mutation 1, Nenad Sestan
• MGI ID: MGI:7425387
• Gene: Cyp26b1 Location: Chr6:84548396-84570890 bp, - strand Genetic Position: Chr6, 36.45 cM
• Alliance: Cyp26b1^em1Nses page

Mutation origin

• Strain of Origin: (C57BL/6J x SJL/J)F1/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination using guide RNAs created a deletion spanning exons 3 to 6. (J:325971)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp26b1 Mutation: 33 strains or lines available

References

• Original: J:325971 Shibata M, et al., Regulation of prefrontal patterning and connectivity by retinoic acid. Nature. 2021 Oct;598(7881):483-488
• All: 1 reference(s)