Gt(ROSA)26Sor^{tm1.1(Tcf/Lef-EGFP*)Knd}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(Tcf/Lef-EGFP*)Knd}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Hisato Kondoh
• MGI ID: MGI:7425297
• Synonyms: R26-WntVis
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(Tcf/Lef-EGFP*)Knd} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307583
• Parent Cell Line: B6-3i/HK3i (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct inserted at the locus seven copies of the TCF/LEF concensus binding site driving expression of an EGFP reporter gene with an H2B nuclear localization sequence. (J:307583)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:307583 Takemoto T, et al., R26-WntVis reporter mice showing graded response to Wnt signal levels. Genes Cells. 2016 Jun;21(6):661-9
• All: 6 reference(s)