Ube3a^em1Alb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ube3a^em1Alb
• Name: ubiquitin protein ligase E3A; endonuclease-mediated mutation 1, Arthur Beaudet
• MGI ID: MGI:7425239
• Synonyms: Ube3a^em1Chjo, Ud6-
• Gene: Ube3a Location: Chr7:58878498-58961284 bp, + strand Genetic Position: Chr7, 33.95 cM
• Alliance: Ube3a^em1Alb page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 6 (1247 nt). (J:324884)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ube3a Mutation: 73 strains or lines available

References

• Original: J:324884 Shi SQ, et al., Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a. Front Behav Neurosci. 2022;16:837523
• All: 2 reference(s)