Mbd2^tm1Amac
Targeted Allele Detail

Summary

• Symbol: Mbd2^tm1Amac
• Name: methyl-CpG binding domain protein 2; targeted mutation 1.1, Andrew S MacDonald
• MGI ID: MGI:7425039
• Gene: Mbd2 Location: Chr18:70701260-70759202 bp, + strand Genetic Position: Chr18, 44.54 cM
• Alliance: Mbd2^tm1Amac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222798
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• The allele consists of loxP sites flanking exon1 of Mbd2. (J:222798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mbd2 Mutation: 21 strains or lines available

References

• Original: J:222798 Cook PC, et al., A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells. Nat Commun. 2015;6:6920
• All: 2 reference(s)